My thoughts are you can expect the stock shafts to last indefinitely and that the lockers are more than good enough.
If you regear, then you might want to consider upgrading shafts due to the added torque. I stayed with stock 4.10 gears and stock shafts for several years (with 35s). Then when I went to 4.88's, I upgraded rear axle shafts at the same time to AlloyUSA ones.
The front ones I am still debating and so far, I haven't been able to justify the costs. I do have a new set of stock shafts as spares but if they do break, I'll upgrade for sure. To what, I'm not exactly sure yet.
If you regear, then you might want to consider upgrading shafts due to the added torque. I stayed with stock 4.10 gears and stock shafts for several years (with 35s). Then when I went to 4.88's, I upgraded rear axle shafts at the same time to AlloyUSA ones.
The front ones I am still debating and so far, I haven't been able to justify the costs. I do have a new set of stock shafts as spares but if they do break, I'll upgrade for sure. To what, I'm not exactly sure yet.